influence of cigarette smoking on the activity of salivary alpha-amylase

نویسندگان

سریری

r sariri department of biochemistry, the university of guilan, rasht, iran غفوری

h ghafoori department of biochemistry, the university of guilan, rasht, iran وارسته

a varasteh department of biochemistry, the university of guilan, rasht, iran عرفانی

a erfani department of internal medicine, iran university of medical sciences,tehran, iran

چکیده

introduction: tobacco smoke is involved in the pathogenesis of several diseases in different body systems. saliva is the first body fluid that confront inhaled cigarette smoke which is injurious to the oral cavity and is associated with several oral diseases and cancer. the aim of our study was to evaluate the influence of smoking on the activity of alpha-amylase in the saliva of healthy smoker individuals. material & methods: alpha-amylase was measured in the supernatant of centrifuged saliva of 25 volunteer smokers, before and just after smoking a single cigarette using the standard chemical methods. results: the enzymatic activity showed a significant inhibition following a single cigarette. reduction in the enzymatic activity of saliva is most probably due to the interaction between smoke aldehydes and –sh groups of the enzyme molecules. conclusions: based on the results obtained from the present study, it could be emphasized that smoking just one cigarette is sufficient to alter the salivary alpha- mylase enzymatic activities.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Influence of Cigarette Smoking on the Activity of Salivary Alpha-Amylase

Introduction: Tobacco smoke is involved in the pathogenesis of several diseases in different body systems. Saliva is the first body fluid that confront inhaled cigarette smoke which is injurious to the oral cavity and is associated with several oral diseases and cancer. The aim of our study was to evaluate the influence of smoking on the activity of alpha-amylase in the saliva of healthy smoker...

متن کامل

the influence of the neo-platonic concept of poetic imagination on wordsworth’s poetry

بر اساس نظریه افلاطون در باره شعر خلاقیت هنری مورد انتقاد قرار گرفته است. نظریه کلی در مورد شعر این بود که شعر از ظواهرتقلید میکند و نه حقیقت. چون سایه ای از حقیقت است. اما با پیدایش فلسفه نو افلاطونی، انتقاتات قبلی در مورد شعر و شاعری اصلاح شد. فلوطین در کتاب انئید، اساس خلق هنری را بر محور مُثل افلاطونی قرار داد. وی باور داشت که هنر مندان در خلق آثار هنری، تحت تاثیر مُثل افلاطونی بوده و عوالمی ...

Effects of cigarette smoke borne reactive nitrogen species on salivary alpha-amylase activity and protein modifications.

Cigarette smoke (CS) is associated with a variety of human pathologies including cardiovascular disease and cancer. Oral squamous cell carcinoma (OSCC) is the most common malignancy of the head and neck. The major inducer of OSCC is exposure to tobacco. Recent studies demonstrated that oxidative and nitrosative stress contributes to the development of oral carcinogenesis through DNA damage. All...

متن کامل

effects of some alpha-amylase inhibitors on the salivary alpha-amylase activity of the stripped bug, graphosoma lineatum (heteroptera: scutelleridae)

abstract digestive enzyme inhibitors are proteinacious or nonproteinacious compounds which reduce an enzyme activity through attaching to its active site and/or its substrate. nowadays, plant enzyme inhibitors are of great importance because 1) these have considerable effects on insect digestive enzymes and as a result on their development; and 2) the transgenic plants expressing them are safe....

متن کامل

Does cigarette smoking influence acne?

Introduction: Acne is a common problem in adolescent and youngage groups, for which several risk factors have been suggested.One of the risk factors is smoking. In studies on the relationshipbetween smoking and acne, conflicting results have been obtained.Method: This study was conducted on 133 male patients whowere visited at the dermatology clinic of Imam Reza hospital dueto acne as the case ...

متن کامل

The Correlation between Cigarette Smoking and Salivary Flow Rate

Background and aim: Side effects of cigarette smoking are among the major concerns. These complications can adversely affect the oral environment. Since reduced salivary flow rate increases the incidence of tooth decay and other dental and oral problems, the present research aimed to investigate the relationship between cigarette smoking and salivary flow rate. Materials and Methods: In this h...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
iranian journal of toxicology

جلد ۲، شماره ۳، صفحات ۲۱۶-۲۲۰

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023